Researchers identify origin of chromosomal oddity in some cancer cells
Wednesday, May 27, 2015 - 18:20
in Biology & Nature
Surveys of the genomic terrain of cancer have turned up a curious phenomenon in some tumor cells: a massive rearrangement of DNA in one or a few chromosomes, thought to be produced during a single cell cycle. In a new study, scientists at Dana-Farber Cancer Institute demonstrate how this sudden, isolated shuffling of genetic material - known as chromothripsis - can occur.