Study reveals how a Rab protein controls HIV-1 replication

Monday, May 4, 2015 - 19:00 in Biology & Nature

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals how a Rab protein that controls intracellular trafficking supports HIV-1 assembly by promoting high levels of an important membrane lipid.

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