A new neural circuit controls fear in the brain

Monday, January 19, 2015 - 17:30 in Health & Medicine

A team of researchers at CSHL has discovered a novel circuit in the mouse brain that controls fear. The red cells are neurons identified by a "trans-synaptic tracing technique" Some people have no fear, like that 17-year-old kid who drives like a maniac. But for the nearly 40 million adults who suffer from anxiety disorders, an overabundance of fear rules their lives. Debilitating anxiety prevents them from participating in life's most mundane moments, from driving a car to riding in an elevator. Today, a team of researchers at Cold Spring Harbor Laboratory (CSHL) describes a new pathway that controls fear memories and behavior in the mouse brain, offering mechanistic insight into how anxiety disorders may arise.

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