Taking the 'mute' off silenced gene may be answer to Angelman syndrome

Monday, December 1, 2014 - 18:50 in Biology & Nature

Most genes are inherited as two working copies, one from the mother and one from the father. However, in a few instances, a gene is imprinted, which means that one copy is silenced. This is called genomic imprinting. If the active copy is mutated, then disease results, even though the silenced gene copy may be normal.

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