Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor

Thursday, April 3, 2014 - 15:30 in Health & Medicine

The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in development of the bone cancer. The research was published today online ahead of print in the journal Cell Reports.

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