Coenzyme rare to bacteria critical to Mycobacterium tuberculosis survival

Monday, March 23, 2009 - 20:49 in Biology & Nature

Coenzyme F420, a small molecule that helps certain enzymes transfer electrons, is found in microorganisms known as methane-producing archaea, some of which thrive in extreme environments. It also helps the bacterium that causes tuberculosis (TB) to survive the defenses of the human immune system. Scientists have now discovered at least one way F420 helps to arm the pathogen.

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