... an anti-virulence factor in Salmonella, knowledge that could be used to design improved Salmonella vaccines. Virulence factors allow a pathogen to thrive in the host and cause disease. An anti- ...
... snapshot" may enlighten scientists to the protein secretion process across membranes and provide a foundation to understanding certain bacterial virulence factors that allow bacteria to cause disease.
... genomics narrowed down the search for Brucella virulence factors to a small group of genes. Of particular interest ... S19 compared with two fully sequenced virulent strains." He added: "Further studies ...
... , a principal investigator at the IMCB, identified peptidoglycan (PGN) — a carbohydrate from bacteria — as a factor responsible for causing the conversion of the otherwise harmless C. albicans to its ...
... by direct binding of a key agr response regulator protein.
The researchers concluded that control of virulence factors by RNAIII and quorum-sensing control of metabolism may have once been separate ...
... cell had no effect on toxin production, suggesting that CO2 activity is not essential to virulence factor induction and that bicarbonate, not CO2, is the signal essential for virulence induction.
"In ...
... to serve their master`s microbial needs. These molecules — called virulence factors — co-opt essential cell functions including the reproduction cycle and cell structure assembly, ...
Certain mean strains of bacteria inject virulent teams of molecules into cells that prepare the way ... disease. Different types of these molecules, called virulence factors, wreak havoc in cells’ basic ...
... IV secretion systems are membrane-spanning transporters that can act as syringes that inject virulence factors into the cells of their hosts (eukaryotes). Once introduced, these virulence factors ...
... Makino said. "But there are more practical reasons why it's important to understand viral virulence factors, particularly when you consider the potential need for treatments. There are viruses similar ...
... of VacA), the vacuoles returned.
“This is the first example of a bacterial virulence factor that uses sphingomyelin as a receptor,” Blanke said. “Only sphingomyelin confers sensitivity to the toxin ...
... the scientists have found evidence that the trigger for the bacteria to start producing these extra virulence factors is turned on very shortly after the biofilm begins to form. Once the scientists ...
... ) and mammalian cells, the scientists were able to identify toxins and other molecules, called virulence factors, made by the bacteria that allow it to infect each type of organism.
By pinning down ...
... well, why do people get AIDS? Because the HIV virus has evolved to encode the protein Vif, known as a "virulence factor," that blocks APOBEC-3G.
With APOBEC-3G out of the ...
... "Pathogenic cells are smart," Nickerson stresses, pointing to their remarkable ability to fine-tune virulence factors in response to subtle environmental cues.
S. typhimurium, Nickerson's pathogen ...