Science news articles about 'target tissue'Personalizing medicine: New research shows potential of targeted therapies for cancer
... an imaging agent, is given as a first injection. When the non-tumor-bound bsMAb has substantially cleared non-target tissues and has reached a maximum level in the tumor, the bsMAb- ... Analysis of alcoholics' brains suggests treatment target
... “If the change happens early, it may explain how the brain adapts and could be a potential treatment target,” he said. “If it shows up later, it could be from the toxic effects of alcohol. We need to ... Killer competition: Neurons duke it out for survival
... biology, neuroscientists at Johns Hopkins have discovered how the target tissue helps newly connected peripheral ... tissues innervated by so-called peripheral neurons coax nerves to grow toward them by ... UC San Diego researchers target tumors with tiny 'nanoworms'
... .
“We are now using nanoworms to construct the next generation of smart tumor-targeting nanodevices,” said Ruoslahti. We hope that these devices will improve the diagnostic imaging of cancer and ... Targeting A Pathological Area Using MRI
... the use of contrast agents, which are like colorants, enabling the contrast between healthy tissue and diseased tissue to be increased. However, the agents currently used clinically do not allow the ... Promising Chinese Herbal Targets Identified For Acute Pancreatitis
... can upregulate sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissue as well as inhibit the elevation of calcium concentration in pancreatic acinar cells while relieving ... Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
... nutrients and oxygen to the tumor mass). The molecular target of HB-19 is nucleolin expressed on the surface ... while displaying no toxicity to normal tissue.
The in vivo antitumoral action of HB-19 ... Gene-expression profiling of the effects of liver toxins
... . It is already known that toxins can be classified using transcriptomic data taken from the primary target tissue or organ. In this new work, researchers set out to see if expression data from blood ... Researchers track Lyme disease spirochetes
... and that spirochete movement appears to play an integral role in dissemination from the blood to target tissue sites.
This use of high-resolution, 3D imaging to visualize the dissemination of a ... Stroke study reveals key target for improving treatment and suggests that Gleevec may help
... off blood supply to the area and starving brain tissue until it begins to die.
Such clots cause 80 ... and PDGF-CC appeared to act on the same target, but that to cause the blood-brain barrier to leak, ... Laser surgery probe targets individual cancer cells
... pulses up to 250 microns deep inside tissue. The system includes a tiny, flexible probe ... deliver nanoparticles to cancer cells or other tissue that we want to target, we would be able to remove hundreds ... Sound medicine
... ) uses interstitial ultrasound applicators that bring the ultrasound source in close contact with the target tissue to be destroyed for efficient heating. Using these probes would allow physicians to ... 'Multi-target' immune therapy improves outcomes of severe lupus nephritis
... involves various parts of the immune system, it is necessary to treat the different immune targets with a combination of immunosuppressant drugs."
One group of patients received this "multi-target" ... U-M study: Herceptin targets breast cancer stem cells
... of the study appear online in the journal Oncogene.
"This work suggests that the reason drugs that target HER2, such as Herceptin and Lapatanib, are so effective in breast cancer is that they target ... TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer
... fatty nanoparticle called a liposome and delivering it intravenously. TG2 is the third protein they have targeted in preclinical research. Sood and Mehta are moving TG2 siRNA toward Phase I clinical ...
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Personalizing medicine: New research shows potential of targeted therapies for cancer
... an imaging agent, is given as a first injection. When the non-tumor-bound bsMAb has substantially cleared non-target tissues and has reached a maximum level in the tumor, the bsMAb- ...Analysis of alcoholics' brains suggests treatment target
... “If the change happens early, it may explain how the brain adapts and could be a potential treatment target,” he said. “If it shows up later, it could be from the toxic effects of alcohol. We need to ...Killer competition: Neurons duke it out for survival
... biology, neuroscientists at Johns Hopkins have discovered how the target tissue helps newly connected peripheral ... tissues innervated by so-called peripheral neurons coax nerves to grow toward them by ...UC San Diego researchers target tumors with tiny 'nanoworms'
... . “We are now using nanoworms to construct the next generation of smart tumor-targeting nanodevices,” said Ruoslahti. We hope that these devices will improve the diagnostic imaging of cancer and ...Targeting A Pathological Area Using MRI
... the use of contrast agents, which are like colorants, enabling the contrast between healthy tissue and diseased tissue to be increased. However, the agents currently used clinically do not allow the ...Promising Chinese Herbal Targets Identified For Acute Pancreatitis
... can upregulate sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissue as well as inhibit the elevation of calcium concentration in pancreatic acinar cells while relieving ...Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
... nutrients and oxygen to the tumor mass). The molecular target of HB-19 is nucleolin expressed on the surface ... while displaying no toxicity to normal tissue. The in vivo antitumoral action of HB-19 ...Gene-expression profiling of the effects of liver toxins
... . It is already known that toxins can be classified using transcriptomic data taken from the primary target tissue or organ. In this new work, researchers set out to see if expression data from blood ...Researchers track Lyme disease spirochetes
... and that spirochete movement appears to play an integral role in dissemination from the blood to target tissue sites. This use of high-resolution, 3D imaging to visualize the dissemination of a ...Stroke study reveals key target for improving treatment and suggests that Gleevec may help
... off blood supply to the area and starving brain tissue until it begins to die. Such clots cause 80 ... and PDGF-CC appeared to act on the same target, but that to cause the blood-brain barrier to leak, ...Laser surgery probe targets individual cancer cells
... pulses up to 250 microns deep inside tissue. The system includes a tiny, flexible probe ... deliver nanoparticles to cancer cells or other tissue that we want to target, we would be able to remove hundreds ...Sound medicine
... ) uses interstitial ultrasound applicators that bring the ultrasound source in close contact with the target tissue to be destroyed for efficient heating. Using these probes would allow physicians to ...'Multi-target' immune therapy improves outcomes of severe lupus nephritis
... involves various parts of the immune system, it is necessary to treat the different immune targets with a combination of immunosuppressant drugs." One group of patients received this "multi-target" ...U-M study: Herceptin targets breast cancer stem cells
... of the study appear online in the journal Oncogene. "This work suggests that the reason drugs that target HER2, such as Herceptin and Lapatanib, are so effective in breast cancer is that they target ...TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer
... fatty nanoparticle called a liposome and delivering it intravenously. TG2 is the third protein they have targeted in preclinical research. Sood and Mehta are moving TG2 siRNA toward Phase I clinical ...