... growth of fat tissue in mice and cell models. Researchers at the Jean Mayer USDA Human ... contributed to angiogenesis progression in both cell and rodent models.
"Again, based on this data, we have no ...
... that involves in vitro tests, animal studies—often with rodent models of disease—and human clinical trials. Inadequately designed rodent studies have led to missteps and delays in previous drug ...
... appears to reduce weight gain in mice and suppress the growth of fat tissue in mice and cell models. Researchers studied mice fed high fat diets supplemented with curcumin and cell cultures incubated ...
... meeting in Chicago. The summary consisted of back-to-back presentations of five studies using a rodent model of brain injury that have either been published this year in various journals or are ...
... that tamoxifen was active against parasites in vitro, the authors now show its efficacy in a rodent model of infection with L. amazonensis.
The Brazilian group, led by Silvia Uliana, observed that ...
... to determine if the relationship between circadian disruption and health outcomes could be uncovered using rodent models.
Twenty rats were exposed to a consistently repeating pattern of 12 hours of ...
... treatment causes long-term cessation of drug taking behavior in rodent models," Nader said.
Previous efforts to expose human addicts to drug-associated cues in the absence of drug ...
... Duke University Medical Center, Durham, using rodent models of biliary fibrosis as well as human ... hedgehog (Hh) pathway. Similarly, in a rat model of biliary fibrosis only cholangiocytes exhibiting high ...
... developing tumors. New data, generated in two rodent models of colon cancer, by François Ghiringhelli ... -dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer
AUTHOR CONTACT: ...
... possibilities for its use as a human vaccine. These studies show how results obtained in rodent models of malaria can be pipelined to form the basis for clinical development of anti-malaria vaccines ...
... called HDAC inhibitors, which have been shown to protect the central nervous system in rodent models of Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis. Clinical trials are ...
... Biology and Medicine. Circulating adiponectin levels are significantly lower in obese humans and rodent models than in lean controls. It is known that excess body weight and elevated body mass ...
... also for treatment of animal diseases. "Large animals offer a link between the classical rodent models and application in the clinic," said Schnieke.
"In view of the close genetic, anatomical and ...
... in dogs, the clinical spectrum in dogs may represent more accurately that of human ALS.
"Compared with the rodent models for ALS, dogs with DM are more similar to people in size, structure and ...
... .
The work may also be significant in terms of understanding the results of much clinical research using rodent models. Infections similar to the chronic H. pylori "are now known to be widespread in ...
