Science news articles about 'p53 levels'

... to reproduce. As such, reactivation of p53 is thought to have great therapeutic potential. Normally, p53 levels are low, but it springs into action in response to DNA damage or activation of cancer- ...

... Trim24 may offer a therapeutic approach to restoring p53 and killing tumor cells," said senior author ... nucleus, and increasing Trim24 expression reduced p53 levels. Loss of Trim24 expression in a breast ...

... whether any miRNAs directly affect p53, Le, who is a joint graduate student in Lodish's ... When Le reduced the amount of miRNA125b in the cells, p53 levels and the number of cells undergoing apoptosis ( ...

... cell. This promoter region is normally regulated by p53, a tumor suppressor gene implicated in as many of 50 ... Part of MDM2's normal function is to inhibit p53 when its levels get too high in a cell. ...