... for Age Research, reports the ability to predict the molecular cause of many inherited genetic diseases. These predictions ... purposes could develop hypotheses about what those mutations are causing on a molecular level; they may also be able to use the tool to correlate ...
... -Farber Cancer Institute say they have identified the root molecular cause of a variety of ills brought on by advanced age, including waning energy, failure of the heart ...
... Zhou, Ph.D., an associate professor of molecular genetics and microbiology in the UF College of Medicine ... into adult neurons. However, the underlying cellular and molecular causes of the transformations were undetected. The latest findings ...
... . Both teams now have evidence to explain what separates the diseases despite their similar molecular causes. They find that XP-causing mutations in XPD all fall ...
... . Research leads to new insights into the molecular causes The molecular story hidden behind schizophrenia ... only after it has been cleaved in the right way. This cleavage is the responsibility of a molecular 'scissors' called Aph1B/C-gamma ...
... of whom showed a one-third difference in expression between the two genes. "We and others must now determine the molecular cause of the difference so that we can begin to design ...
... from gene to disease that psychiatrists pray for," says Cascella. "This is a molecular pathway that we can potentially target for drug therapy ... to sub-stratify psychiatric illness into discrete molecular causes," adds Katsanis. "Now that we know ...
... Lowe of Cold Spring Harbor Laboratory. "If we understand cancer, we can treat it better by going after the molecular causes or by categorizing cancers to better predict ...
Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown ... mouse models through which they can determine whether there are molecular pathways by which senescent cells can either be safely ...
... that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also account for some inherited ... . Our findings represent a new way to look for the molecular cause of disease, and eventually may lead to improved ...
... myocardial infarction. For many years, it was unclear what causes the elevated blood fat levels in this ... Stephan Herzig, head of the Research Group "Molecular Metabolic Control" at the German Cancer ...
Scientists have discovered a mechanism in liver metabolism that is responsible for pathologically elevated blood fat levels found in severe metabolic disorders. Mice suffering from metabolic syndrome ...
... that causes seasonal human infections; this is really remarkable," said Ruben Donis, PhD, chief of the Molecular ... for Medical Research is dedicated to revealing the fundamental molecular causes of disease and devising the innovative therapies ...
... active Ago2 hampers their normal postnatal development." Cheloufi and her colleagues have traced a molecular cause of this lethal defect to a single microRNA ...
... from Munich, Marburg, Frankfurt and Lausanne, has investigated the molecular causes of this phenomenon. They discovered that the production of the COX ... by boosting the COX-2 production in mice using a molecular-biological trick. The body weight of these animals ...