Dr. Gleason devised the Gleason score, which has been used to help determine the aggressiveness of prostate cancer in millions of men.
Dr. Donald F. Gleason, the Minnesota pathologist who developed the Gleason score that is now used almost universally in the U.S. to predict the likely outcome of prostate cancer, died Dec. 28 of a ...
... with prostate cancer know their Gleason score, a
measure of malignancy. The scoring system was invented by Donald
... harder still
to evaluate new therapies. Gleason's system worked, because he
involved ...
... finasteride was associated with significant declines in tumors with Gleason scores 5, 6 and 7, which comprise ... scores of 8, 9 and 10, the incidence for men taking finastride was no higher than for men ...
... features such as rapid PSA doubling time or high Gleason score [a grading system for prostate cancer] may benefit from salvage radiotherapy," the authors write.
"… our data provide the ...
... , Shariat says. Urologists currently use a risk predictor that includes variables like stage, Gleason score and serum levels of prostate-specific antigen. "However, this method is only accurate about ...
... , but considered high-risk (i.e. pre-treatment PSA ≥ 20, Gleason score 8-10, or larger tumors palpable during digital rectal exam) and looked at outcomes with and without ...
... with 1.5% in year three.
Cancers picked up at baseline were also more likely to have a higher Gleason score, meaning that the cancer was more aggressive and more likely to be fatal. 34% had a ...
... general population is very low; and men with high Gleason scores already know that their prostate cancer is ... men diagnosed with early-stage (low Gleason score) prostate cancers–particularly Ashkenazi ...
... the men, we found that 22 percent of them experienced an increase in their Gleason score—meaning that they had a more aggressive cancer than was originally thought from their original biopsy. The 3-D ...
... (PSA) below 10 ng/ml; clinical stage T1-T2a; Gleason score 6 or below; and 3 or fewer positive cores at diagnostic biopsy. In addition, participants underwent a restaging biopsy ...
... the routine-care group had more aggressive tumors (Gleason score 8-10). The reduced number of men with prostate cancer with a Gleason score of 8-10 in the intervention group may eventually lead to ...
... a PSA doubling time of less than three years, Gleason score progression (to 4+3 or greater) or ... PSA doubling time of less than three years or Gleason upgrading. Of the 137 patients treated surgically, ...
... prostate cancer is closely related to a man's PSA score; a baseline PSA level above the median for ... .0 ng/mL or when locally advanced or when the Gleason score is greater than or equal to 8. Pelvic ...
... PSA levels based on age, BMI and Gleason score, a classification of the grade and stage of prostate ... , however, were not significantly lower in patients taking statins for Gleason 6 and Gleason 8-10, ...
