... a commentary published online May 27 in the Journal of the National Cancer Institute. Radiation and many chemotherapy agents work to kill cells by inducing free radicals that damage DNA and proteins. ...
... from McGill University's Faculty of Medicine have discovered a compound that reduces resistance to chemotherapy agents used to treat cancer. Their results were published in the June issue of The ...
... from McGill University's Faculty of Medicine have discovered a compound that reduces resistance to chemotherapy agents used to treat cancer. Their results were published in the June issue of The ...
A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced non-small cell lung cancer, according to a ...
Researchers are describing progress toward developing a new generation of chemotherapy agents that target and block uncontrolled DNA replication - a hallmark of cancer, viral infections, and other ...
... in cancer cells similar to the way estrogen does—by inducing proteins that protect the cells from chemotherapy agents.
Estrogen's protein-inducing action has been previously linked to chemotherapy ...
The combination of traditional chemotherapy agents with targeted therapies called monoclonal antibodies showed no safety concerns and improved survival in patients with advanced non-small cell lung ...
... -based quantification of "leakiness" is closely correlated to the ability of a clinically approved chemotherapy agent to enter the tumor, allowing the researchers to predict the agent's therapeutic ...
... other cancers, before now, there's been little research to quantify the use of off label chemotherapy agents and their impact, said Giordano.
"Off labels run a dramatic spectrum - sometimes there's ...
Though the growing shift toward oral chemotherapy agents offers cancer patients greater ... insurance coverage for these expensive oral chemo agents is spotty, leaving many patients to pay a substantial ...
... did not have improved outcomes compared to patients who received 5FU alone.
"We found that adding chemotherapy agents to the standard 5FU regimen in older patients after surgery did not provide the ...
... and magnesium in reducing neurotoxicity caused by other medications,” says Dr. Nikcevich. “Many other commonly used chemotherapy agents cause neurological sensitivity. By applying our study design, we ...
... involved in 'pumping' drugs out of cells thereby reducing the effectiveness of cancer chemotherapy agents and antibiotics among other drugs."
"By understanding how these membrane proteins work, we ...
... .
MNNG, a DNA-damaging compound similar to toxic chemicals found in tobacco smoke and in common chemotherapy agents, usually kills cells by inducing irreparable DNA damage. However, the researchers ...
... emergent technology, for sustained drug release.
The researchers demonstrated that the device releases the chemotherapy agent Doxorubicin in a sustained and consistent manner -- a requirement of any ...
