... genes have long been known to specify distinct cell types along the developing body axes ... downstream gene transcription to form specific cells or tissues. In what the researchers called "an unexpected ...
... Cell, scientists report that the same transcription factor, which is crucial for the survival of different stem cell types, can behave differently. This study clearly showed for the first time that ...
... report that the same transcription factor, which is crucial for the survival of different stem cell types, can behave differently. This finding reveals important insights about how scientists may be ...
... the living animal and minimizing degradation. Alternative approaches to getting the profiles of cell types in complex tissues have been disappointing because they require the physical isolation of ...
... diseases seem to know exactly what types of cells to attack. While decimating one cadre ... molecular differences among the hundreds of specialized cell types that are tangled together in tissues like ...
... and Tumor Cell Biology. Differentiation is the process by which genetic activity causes an immature cell type to acquire specific characteristics of a particular mature adult cell type.
"In the ...
Scientists have discovered that a certain differentiated cell type is so ready to change its identity that it requires the constant expression of a gene called Prox1 to dissuade it.
... . These patterns suggested that enhancers are of primary importance in the differentiation of specific cell types."
Using previously described chromatin signatures for enhancers, the scientists ...
... , short regions of DNA that act to enhance or boost the expression of genes. The map will help scientists understand how cells control expression of genes specific to their particular cell type.
... to another, we thought we could nudge differentiated cells from one type to another through the use of the RNA population. So, ... Eberwine. "While the cells don't look like neurons any longer, they don' ...
... cell, described in an article published April 24 in the open access journal PLoS Pathogens ... form of the disease and sometimes die.
"Targeting this cell type may lead to new drugs and immunotherapeutics ...
... the laboratory will eventually give rise to a few cells that look and act like embryonic stem ... cause them to directly change into other cell types by putting them with various mesenchymes and growing ...
... researcher Alice Gerrits has shown how variations in the genome can influence the activity of genes. This effect was found to be strongly dependent on the cell type in which these genes were active.
... Miodrag Stojkovic, co-editor of Stem Cells. “For the first time, scientists from UCLA were able ... already partially transformed into specific cardiac cell types may prevent tumor growth. The use of iPS ...
... through programmed cell death (apoptosis).”
“Such specific regulation of autophagy may also be important for cell types in the muscle, brain and pancreas,” said Dr. Min Chen, assistant professor of ...
