... if ARV-based microbicides that could cause moderate to high levels of drug resistance might pass ... microbicides could pass Phase III trials, as their potential to cause resistance will be masked by frequent testing ...
Activation of the Src signaling pathway may cause resistance to standard medical treatment in some patients with breast ... , and inhibition of this pathway holds the potential to overcome that resistance, according to data presented here at the American Association ...
... inhibitors, people living with HIV generally will not have resistance to maraviroc because they have not been exposed to any drugs ... in the virus's genetic make-up are called mutations. It's these mutations that cause resistance to HIV medications. Often ...
European researchers have found that metastatic colorectal cancer patients with a mutation in the BRAF gene do not respond to anti-EGFR therapy with cetuximab and panitumumab. The finding could help ...
... years that low-oxygen, or hypoxic, cells cause resistance to radiation therapy," said senior co ... hypoxic tumor cells have been identified as a cause of treatment resistance for decades, there has not been a reliable method to kill ...
... from killing them. Scientists have discovered that the mutations that caused resistance to chloroquine and pyrimethamine originated in Asia ... how they spread across the continent. However, the mutations that cause resistance to sulfadoxine only began to emerge in the mid ...
... and fat, a process called insulin resistance." Insulin, a hormone produced in the pancreas, ... turn it into energy. Different types of diabetes are caused by the body's inability to produce sufficient ...
... in the lungs become narrow, blocked or destroyed causing resistance to blood to flow. As the pressure builds, the heart's lower right chamber becomes overworked ...
... point will stop--thanks to viscous drag which causes resistance to the motion. "Let me explain ... , moves through air or liquid, it will resist the motion. This resistance is caused by viscous drag. Or look ...
... of proteins related to the malaria parasite protein, which causes resistance to the front-line drug chloroquine ... a novel tool for studying the malarial chloroquine-resistance factor. The study examined transporter proteins ...
... of the other antibiotics. Finally, they sequenced the genes known to cause resistance to each antibiotic and pinpointed the mutations ... by the antibiotic that produced the mutation but, as a result of its mutation, be resistant to other antibiotics." The group's findings underscore the potentially ...
... an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly ... cancer, Chen said, but over time the disease becomes resistant and progresses. Scientists have known that the protein complex ...
... until the lumen of the bile duct is narrowed to cause resistance to the flow of bile. Bile is a fluid secreted by the liver via the bile ducts and is concentrated ...
... how this latest class of drug works and what causes resistance to it, we can better select other classes of drugs ... of HCV therapy and the key to overcoming drug resistance." The groundbreaking research is described in a paper published ...
... ARV drug or drugs are being used in that strategy. As a result, resistance to that drug could emerge. (Use of an antiretroviral in someone who is not infected with HIV cannot cause resistance.) iPrEx trial participants were tested ...
