Science news articles about 'broken chromosomes'

  • How cells handle broken chromosomes

    ... by the cellular machinery, the broken chromosome is extensively scanned for homology ...
  • How Cells Handle Broken Chromosomes

    ... by the cellular machinery, the broken chromosome is extensively scanned for homology ...
  • To understand chromosome reshuffling, look to the genome's 3D structure

    ... great influence over where broken chromosome ends rejoin, knowledge ... they found that broken chromosomes often rearrange within themselves ... "Our finding that broken chromosome segments are more likely ...
  • Why chromosomes never tie their shoelaces

    ... the protective tips of chromosomes: while broken chromosome ends generated by DNA ... the tips of chromosomes were recognized as broken DNA, cells ... at the tips of chromosomes - stop this from happening ...
  • 'Pulverized' chromosomes linked to cancer?

    ... could potentially disrupt the chromosomes within them and produce ... which DNA damage and broken chromosomes cause cancer is well ... that, unexpectedly, whole chromosome aneuploidy might promote cancer ...
  • Safeguarding genome integrity through extraordinary DNA repair

    ... gene mutations but broken chromosomes and chromosomal abnormalities known to ... "They can promote chromosome aberrations, with severe ... recombination between different chromosomes, and promoting safe ...
  • Worm genes KO'd

    ... normally uses the undamaged twin chromosome as a template for ... and C. By "repairing" the broken chromosome, the new method can delete ... of the location where the chromosome is broken. But that still means ...
  • Key protein aids in DNA repair

    ... in the form of a broken chromosome, or double strand break, ... – called nucleotides," he notes. Broken chromosomes can be compared to a ... removes the "dirt" at broken chromosome ends, allowing for much more ...
  • Unusual mechanism of DNA synthesis could explain genetic mutations

    ... of DNA damage. When chromosomes experience double-strand breaks ... utilize their genetically similar chromosomes to patch the gaps via ... of the broken molecules. To repair a broken chromosome that lost ...
  • A needle in a haystack: How does a broken DNA molecule get repaired?

    ... , the DNA double helix gets broken: both strands are accidentally cut ... a filamentous structure on the broken DNA end. Second, this filament ... DNA or the second DNA chromosome (remember that we have two ...
  • Sending out an SOS: How telomeres incriminate cells that can't divide

    ... anything that resembles a broken chromosome. If repair is impossible ... might mistake exposed chromosome ends for broken DNA. Initially, the ... says, "Without it, chromosomes could become unstable and could ...
  • Sex disorders linked to Y chromosome's instability

    ... , the apparatus for partitioning chromosomes becomes very confused," Page ... result, the chromosome has a tendency to get broken or lost ... For one, unlike other chromosomal abnormalities, the incidence of ...
  • Broken genomes behind breast cancers

    ... genome in some cancers have broken and also the processes that ... cancer cell in gluing the broken bits of genome back together ... the joining of two different chromosomes. Dissecting out the complexity and ...
  • Chromosome number changes in yeast

    ... an unprecedented view of chromosome complement (chromosome number) changes in a ... a chromosome and the subsequent fusion of the two broken ... edges to two different chromosome ends. Although ...
  • Clues to chromosome crossovers

    ... , pregnancy miscarriage or chromosomal diseases such as Down ... , in which chromosomes are first broken and then repaired ... by coupling with a matching template chromosome ...

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