Science news articles about 'FANCM'

  • FANCM plays key role in inheritance

    ... cells that are not involved in reproduction. "We have now proven that FANCM does not only ensure genome stability in somatic ... author of the publication in The Plant Cell. According to the findings, FANCM plays a key role in the combination of paternal ...
  • Molecular anchor links the 2 inheritable diseases Fanconi anemia and Bloom's syndrome

    ... that a disruption of the interaction between the two core complexes and FANCM led to similar chromosomal repair defects ... and FA cells. "We have shown for the first time that FANCM acts as a molecular scaffold that functions in a variety ...
  • Newly identified proteins critical to FA pathway DNA repair function

    ... . In fact, when the researchers suppressed MHF1, it destabilized FANCM and caused increased chromosome aberrations after exposure ... the development of cancers are still being uncovered. The identification of FANCM as part of the FA core complex and its DNA ...

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