Novel blood-based protein signature determined for rare, aggressive lung cancer
Researchers have discovered a panel of 13 blood proteins that may be effective biomarkers to detect malignant mesothelioma, according to a study published Oct. 3 in the open access journal PLOS ONE by Rachel Ostroff from the company SomaLogic, which developed the new test, and colleagues at other institutions. Malignant mesothelioma is a rare, aggressive form of lung cancer that can develop after prolonged exposure to asbestos. Because early diagnosis is difficult, most patients face a poor prognosis and have few options for treatment. In the study, authors compared proteins in the blood of asbestos-exposed individuals without the disease to blood proteins in asbestos-exposed mesothelioma patients to identify 13 proteins that are linked to the disease, including in the early stages.
According to the researchers, the discovery of the new blood-based proteins linked to the disease could help to develop better, less invasive diagnostic tests to detect the disease at earlier stages.
"By measuring changes in blood concentration of a series of proteins we can potentially catch mesothelioma at an earlier stage," said Ostroff, Clinical Research Director at SomaLogic. "Our efforts are now focused on further development of this approach, and how best to get it rapidly into clinical use for the sake of individuals who can benefit from earlier detection of this devastating disease."
Source: Public Library of Science
- Novel blood-based protein signature determined for rare, aggressive lung cancerfrom Science DailyWed, 3 Oct 2012, 21:00:25 EDT
- A simple blood test could be used to detect breast cancer; New clinical study launchedfrom Science DailyTue, 2 Oct 2012, 10:01:01 EDT
Latest Science NewsletterGet the latest and most popular science news articles of the week in your Inbox! It's free!
Learn more about
Check out our next project, Biology.Net
From other science news sites
Popular science news articles
- Exposure to air pollution 30 years ago associated with increased risk of death
- Rare bumble bee may be making a comeback in Pacific northwest
- Americans recognize 'past presidents' who never were, study finds
- Study accurately dates coral loss at Great Barrier Reef
- Horses can read human emotions, University of Sussex research shows
- Cornell researchers create first self-assembled superconductor
- Bacteria critical to early immune development partly restored in infants born by C-section
- New research replicates a folding human brain in 3-D
- New biomarker to assess stem cells developed
- New stem cell model valuable tool for studying Andersen's syndrome