Novel blood-based protein signature determined for rare, aggressive lung cancer
Researchers have discovered a panel of 13 blood proteins that may be effective biomarkers to detect malignant mesothelioma, according to a study published Oct. 3 in the open access journal PLOS ONE by Rachel Ostroff from the company SomaLogic, which developed the new test, and colleagues at other institutions. Malignant mesothelioma is a rare, aggressive form of lung cancer that can develop after prolonged exposure to asbestos. Because early diagnosis is difficult, most patients face a poor prognosis and have few options for treatment. In the study, authors compared proteins in the blood of asbestos-exposed individuals without the disease to blood proteins in asbestos-exposed mesothelioma patients to identify 13 proteins that are linked to the disease, including in the early stages.
According to the researchers, the discovery of the new blood-based proteins linked to the disease could help to develop better, less invasive diagnostic tests to detect the disease at earlier stages.
"By measuring changes in blood concentration of a series of proteins we can potentially catch mesothelioma at an earlier stage," said Ostroff, Clinical Research Director at SomaLogic. "Our efforts are now focused on further development of this approach, and how best to get it rapidly into clinical use for the sake of individuals who can benefit from earlier detection of this devastating disease."
Source: Public Library of Science
- Novel blood-based protein signature determined for rare, aggressive lung cancerfrom Science DailyWed, 3 Oct 2012, 21:00:25 EDT
- A simple blood test could be used to detect breast cancer; New clinical study launchedfrom Science DailyTue, 2 Oct 2012, 10:01:01 EDT
Latest Science NewsletterGet the latest and most popular science news articles of the week in your Inbox! It's free!
Learn more about
Check out our next project, Biology.Net
From other science news sites
Popular science news articles
- Mediterranean diet associated with lower risk of death in cardiovascular disease patients
- Making pesticide droplets less bouncy could cut agricultural runoff
- Quest to find the 'missing physics' at play in landslides
- New optical material offers unprecedented control of light and thermal radiation
- People enhanced the environment, not degraded it, over past 13,000 years
- Gene therapy via ultrasound could offer new therapeutic tool
- Typhoon Lionrock threatening Japan
- US teens more likely to vape for flavorings than nicotine in e-cigarettes
- 3-D-printed structures 'remember' their shapes
- Structural, regulatory and human error were factors in Washington highway bridge collapse
- Interscatter enables first implanted devices, contact lenses, credit cards to 'talk' WiFi
- Why do they treat me like that? Taking the mask off of envy
- New study reveals a novel protein linked to type 2 diabetes
- Duration of adulthood overweight and obesity linked to cancer risk in US women
- Diabetes drug may also offer vascular protection